Zi ZT and Rao Y (2024). Discoveries of GPR39 as an evolutionarily conserved receptor for bile acids and of its involvement in biliary acute pancreatitis. Sci Adv 10:eadj0146.
Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiology.
Bian XL, Zhu JM, XB, Liang WJ, Yu SH and Rao Y.
eLife, 2023, 12:RP89317 (bioRxiv 2022.12.22.521565).
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Importance of glutamine in synaptic vesicles revealed by functional studies of SLC6A17 and its mutations pathogenic for intellectual disability.
Jia X, Zhu J, Bian X, Liu S, Yu S, Liang W, Jiang L, Mao R, ZhangW and Rao Y.
eLife, 2023, 12:RP86972.
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Sleep need, the key regulator of sleep homeostasis, is both indicated and controlled by phosphorylation of threonine 221 in salt inducible kinase 3.
Li Y, Li CG, Liu YX, Yu JJ, Yang JQ, Cui YF, Wang TV, Li CY, Jiang LF, Song ML and Rao Y
Genetics, 2023, 224:iyad136
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ppGpp is present in, and functions to regulate sleep of, Drosophila.
Dai X, Yang W, Zhang X, Zhou E, Liu Y, Wang T, Zhang WX, Zhang XX and Rao Y (2023).
hLife, 2023, 1:98-114 (bioRxiv 2022.11.17.516975).
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Molecular and cellular mechanisms of the first social relationship: A conserved role of 5-HT from mice to monkeys, upstream of oxytocin
Liu Y#, Shan L, Liu T, Li J, Chen Y, Sun C, Yang C, Bian X, Niu Y, Zhang C, Xi J, Rao Y#
Neuron. 2023 Feb 25:S0896-6273(23)00114-9
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LKB1 is physiologically required for sleep from Drosophila melanogaster to the Mus musculus
Liu ZY, Jiang LF, Li CY, Li CG, Yang JQ, Yu JJ, Mao RB and Rao Y
Genetics 221, iyac082.
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STE20 phosphorylation of AMPK related kinases revealed by biochemical purifications combined with genetics
Liu YX, Wang TV, Cui YF, Li CY, Jiang LF and Rao Y
J Biol Chem 298, 101928.
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Biochemical purification uncovers mammalian sterile 3 (MST3) as a new protein kinase for multifunctional protein kinases AMPK and SIK3
Liu YX, Wang TV, Cui YF, Gao SX and Rao Y
J Biol Chem 298, 101929.
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Molecular resolution of a behavioral paradox: sleep and arousal are regulated by distinct acetylcholine receptors in different neuronal types in Drosophila
Xihuimin Dai*#, Enxing Zhou*, Wei Yang, Renbo Mao, Wenxia Zhang and Yi Rao
Sleep, 2021 advance article
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Heritability of human visual contour integration—an integrated genomic study
Zijian Zhu*, Biqing Chen*, Ren Na*, Wan Fang, Wenxia Zhang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Yi Rao#, and Fang Fang#
European Journal of Human Genetics, Published online: 30 July 2019
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The First Hormone: Adrenaline
Yi Rao
D-Serine Made by Serine Racemase in Drosophila Intestine Plays a Physiological Role in Sleep
Xihuimin Dai*, Enxing Zhou*, Wei Yang, Xiaohui Zhang, Wenxia Zhang, and Yi Rao
Nature Communications (2019) 10:1986
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Chemoconnectomics: Mapping Chemical Transmission in Drosophila
Bowen Deng*, Qi Li*, Xinxing Liu*, Yue Cao*, Bingfeng Li, Yongjun Qian, Rui Xu, Renbo Mao, Enxing Zhou, Wenxia Zhang, Juan Huang, and Yi Rao
Neuron, 2019, 101: 876–893
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Genomic Analyses of Visual Cognition: Perceptual Rivalry and Top-Down Control
Biqing Chen*, Zijian Zhu*, Ren Na*, Wan Fang, Wenxia Zhang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Fang Fang,and Yi Rao
The Journal of Neuroscience, 2018, 38(45): 9668 –9678
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Multi-level genomic analyses suggest new genetic variants involved in human memory
Zijian Zhu*#, Biqing Chen*#, Hongming Yan, Wan Fang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Tianming Gao, Liang Chen, Jieyu Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Wenxia Zhang and Yi Rao
Eur J Hum Genet, published online July 3rd, 2018
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Thermoregulation-Independent Regulation of Sleep by Serotonin Revealed in Mice Defective in Serotonin Synthesis
Xian Zhang*, Hongming Yan*, Yanjia Luo, Zili Huang and Yi Rao
Mol Pharmacol, 2018, 93:657-664.
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Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity
Biqing Chen*, Zijian Zhu*, Yingying Wang, Xiaohu Ding, Xiaobo Guo, Mingguang He, Wan Fang, Qin Zhou, Shanbi Zhou, Han Lei, Ailong Huang, Tingmei Chen, Dongsheng Ni, Yuping Gu, Jianing Liu, Yi Rao
Journal of Human Genetics, 2018, Advance Online
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Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila
Yongjun Qian, Yue Cao , Bowen Deng, Guang Yang , Jiayun Li, Rui Xu , Dandan zhang , Juan Huang, Yi Rao
eLife , 2017 , 6:e26519
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Cue-independent memory impairment by reactivation-coupled interference in human declarative memory
Zijian Zhu, Yingying Wang, Zhijun Cao, Biqing Chen, Huaqian Cai, Yanhong Wu, Yi Rao
Cognition,155 (2016) 125–134
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Serotonin signaling in the brain of adult female mice is required for sexual preference
Shasha Zhang, Yan Liu, Yi Rao
Proc Natl Acad Sci USA , 2013 , 110: 9968-9973.
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Molecular Genetic Analysis of Sexual Rejection: Roles of Octopamine and Its Receptor OAMB in Drosophila Courtship Conditioning
Chuan Zhou*, Hai Huang*, Susy M. Kim*, Hsuanwen Lin, Xianglan Meng, Kyung-An Han, Ann-Shyn Chiang, Jing W. Wang, Renjie Jiao and Yi Rao#
Journal of Neuroscience, 2012
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Social regulation of aggression by pheromonal activation of Or65a olfactory neurons in Drosophila
Weiwei Liu, Xinhua Liang, Jianxian Gong, Zhen Yang, Yao-Hua Zhang, Jian-Xu Zhang and Yi Rao
Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice
Yan Liu, Yun`ai Jiang, Yunxia Si, Ji-Young Kim, Zhou-feng Chen and Yi Rao
A subset of octopaminergic neurons are important for Drosophila aggression
Chuan Zhou, Yong Rao, and Yi Rao
Nature Neurosci 11:1059-1061 (2008)
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Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling.
Li X, Gao X, Liu G, Xiong W, Wu J, Rao Y
Nature Neuroscience (2008)
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Role of the integrin-linked kinase (ILK) in determining neuronal polarity
Guo W, Jiang H, Gray V, Dedhar S, and Rao Y
Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3b and its upstream regulators.
Jiang H., Guo W., Liang X.H., and Rao Y
Cell (2005)
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Commentary in Current Biology by Rong Li PDF
Netrin requires the focal adhesion kinase and the Src family kinases to induce axon outgrowth and to attract axons.
Liu G., Beggs H., Jürgensen C., Park H.T., Tang H., Gorski J., Jones K.R., Reichardt L.F., Wu J.Y., and Rao Y
Nature Neurosci (2004)
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Visualization of spatially and temporally regulated N-WASP activity during cytoskeletal reorganization in living cells.
Ward M.E., Wu J.Y. and Rao Y.
Proc Natl Acad Sci USA (2004)
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Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons.
Zhu Y., Yu T., Zhang X-C, Nagasawa T., Wu J.Y., and Rao Y.
Signal Transduction in Neuronal Migration: Roles of GTPase Activating Proteins and the Small GTPase Cdc42 in the Slit-Robo Pathway.
Wong K., Ren X-R, Huang Y-Z, Xie Y., Liu G., Saito H., Tang H., Wen L., Brady-Kalnay S.M., Mei L., Wu J.Y., Xiong W-C, and Rao Y.
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
Wu J.Y., Feng L., Park H-T, Havlioglu N., Wen L., Tang H., Bacon K.B., Jiang Z., Zhang X-C, and Rao Y.
Nature (2001)
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Directional guidance of neuronal migration in the olfactory system by the protein Slit.
Wu W., Wong K., Chen J.H., Jiang Z.H., Dupuis S., Wu J.Y., and Rao Y.
Nature (1999)
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Vertebrate Slit, a secreted ligand for the transmembrane protein Roundabout, is a repellent for olfactory bulb axons
Li H.S., Chen J.H., Wu W., Fagaly T., Yuan W.L., Zhou L., Dupuis S., Jiang Z., Nash W., Gick C., Ornitz D., Wu J.Y., and Rao Y.
Cell (1999)
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Minireview in Neuron D. Van Vactor and J.G. Flanagan PDF
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A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal mesoderm.
Li H.S., Tierney C., Wen L., Wu J.Y. and Rao Y.
Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins.
Rao Y., Jan L.Y., and Jan Y.N.
